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Ampulla of Vater

Primary Tumor (T)
T Category Stage Category Definitions
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
Tis Carcinoma in situ
T1 Tumor limited to ampulla of Vater or sphincter of Oddi
T2 Tumor invades duodenal wall
T3 Tumor invades pancreas
T4 Tumor invades peripancreatic soft tissues or other adjacent organs or structures other than pancreas

Regional Lymph Nodes (N)
N Category Stage Category Definitions
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Regional lymph node metastasis

Distant Metastasis (M)
M Category Stage Category Definitions
M1 Distant metastasis
No distant metastasis (no pathologic M0; use clinical M to complete stage group)

Anatomic Stage/Prognostic Groups
Stage T N M
0 Tis N0 M0
IA T1 N0 M0
IB T2 N0 M0
IIA T3 N0 M0
IIB T1 N1 M0
IIB T2 N1 M0
IIB T3 N1 M0
III T4 Any N M0
IV Any T Any N M1