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Malignant Melanoma of the Conjunctiva

Primary Tumor (T)
T Category Stage Category Definitions
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
Tis Melanoma confined to the conjunctival epithelium
pT1a Melanoma of the bulbar conjunctiva not more than 0.5 mm in thickness with invasion of the substantia propria
pT1b Melanoma of the bulbar conjunctiva more than 0.5 mm but not more than 1.5 mm in thickness with invasion of the substantia propria
pT1c Melanoma of the bulbar conjunctiva greater than 1.5 mm in thickness with invasion of the substantia propria
pT2a Melanoma of the palpebral, forniceal or caruncular conjunctiva not more than 0.5 mm in thickness with invasion of the substantia propria
pT2b Melanoma more than 0.5 but not greater than 1.5 mm in thickness with invasion of the substantia propria.
pT2c Melanoma of the palpebral, forniceal or caruncular conjunctiva greater than 1.5 mm in thickness with invasion of the substantia propria.
pT3 Melanoma invades the eye, eyelid, nasolacrimal system, sinuses or orbit
pT4 Melanoma invades the central nervous system
Quadrants are defined by clock hour, starting at the limbus (e.g. 6, 9, 12, 3) extending from the central cornea to and beyond the eyelid margins. This will bisect the caruncle.
*pT(is) Melanoma in situ (includes the term primary acquired melanosis) with atypia replacing greater than 75 % of the normal epithelial thickness, with cytologic features of epithelioid cells, including abdundant cytoplasm, vesicular nuclei or prominent nucleoli, and/or presence of intraepithelial nests of atypical cells.

Regional Lymph Nodes (N)
N Category Stage Category Definitions
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis, biopsy performed
N1 Regional lymph node metastasis

Distant Metastasis (M)
M Category Stage Category Definitions
M1 Distant metastasis
No distant metastasis (no pathologic M0; use clinical M to complete stage group)

Anatomic Stage/Prognostic Groups
Stage T N M
No stage grouping is presently recommended