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TNM and Stage Groupings > Malignant Melanoma of the Conjunctiva
Malignant Melanoma of the Conjunctiva
Primary Tumor (T)
| T Category |
Stage Category Definitions |
| TX |
Primary tumor cannot be assessed |
| T0 |
No evidence of primary tumor |
| Tis |
Melanoma confined to the conjunctival epithelium |
| pT1a |
Melanoma of the bulbar conjunctiva not more than 0.5 mm in thickness with
invasion of the substantia propria |
| pT1b |
Melanoma of the bulbar conjunctiva more than 0.5 mm but not more than 1.5
mm in thickness with invasion of the substantia propria |
| pT1c |
Melanoma of the bulbar conjunctiva greater than 1.5 mm in thickness with
invasion of the substantia propria |
| pT2a |
Melanoma of the palpebral, forniceal or caruncular conjunctiva not more than
0.5 mm in thickness with invasion of the substantia propria |
| pT2b |
Melanoma more than 0.5 but not greater than 1.5 mm in thickness with invasion
of the substantia propria. |
| pT2c |
Melanoma of the palpebral, forniceal or caruncular conjunctiva greater than 1.5
mm in thickness with invasion of the substantia propria. |
| pT3 |
Melanoma invades the eye, eyelid, nasolacrimal system, sinuses or orbit |
| pT4 |
Melanoma invades the central nervous system |
Quadrants are defined by clock hour, starting at the limbus (e.g. 6, 9, 12, 3) extending
from the central cornea to and beyond the eyelid margins. This will bisect the caruncle.
*pT(is) Melanoma in situ (includes the term primary acquired melanosis) with
atypia replacing greater than 75 % of the normal epithelial thickness, with
cytologic features of epithelioid cells, including abdundant cytoplasm,
vesicular nuclei or prominent nucleoli, and/or presence of intraepithelial
nests of atypical cells.
Regional Lymph Nodes (N)
| N Category |
Stage Category Definitions |
| NX |
Regional lymph nodes cannot be assessed |
| N0 |
No regional lymph node metastasis, biopsy performed |
| N1 |
Regional lymph node metastasis |
Distant Metastasis (M)
| M Category |
Stage Category Definitions |
| M1 |
Distant metastasis |
No distant metastasis (no pathologic M0; use clinical M to complete stage group)
Anatomic Stage/Prognostic Groups
| Stage |
T |
N |
M |
|
|
|
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No stage grouping is presently recommended