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Cutaneous Squamous Cell / Other Cutaneous Carcinoma

Primary Tumor (T)
T Category Stage Category Definitions
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
Tis Carcinoma in situ
T1 Tumor 2 cm or less in greatest dimension with less than two high risk features**
T2 Tumor greater than 2 cm in greatest dimension or
Tumor any size with two or more high risk features*
T3 Tumor with invasion of maxilla, orbit, or temporal bone
T4 Tumor with invasion of skeleton (axial or appendicular) or perineural invasion of skull base
* Excludes cSCC of the eyelid.
**High Risk Features for the Primary Tumor (T) Staging :
Depth/Invasion: > 2 mm thickness, Clark level ≧ IV, Perineural invasion
Anatomic Location: Primary site ear, Primary site hair-bearing lip
Differentiation: Poorly differentiated or undifferentiated

Regional Lymph Nodes (N)
N Category Stage Category Definitions
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimension
N2 Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension; or in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension; or in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension
N2a Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than 6 cm in greatest dimension
N2b Metastasis in multiple ipsilateral lymph nodes, none more than 6 cm in greatest dimension
N2c Metastasis in bilateral or contralateral lymph nodes, none more than 6 cm in greatest dimension
N3 Metastasis in a lymph node, more than 6 cm in greatest dimension

Distant Metastasis (M)
M Category Stage Category Definitions
M1 Distant metastasis
No distant metastasis (no pathologic M0; use clinical M to complete stage group)

Anatomic Stage/Prognostic Groups
Stage T N M
0 Tis N0 M0
I T1 N0 M0
II T2 N0 M0
III T3 N0 M0
III T1 N1 M0
III T2 N1 M0
III T3 N1 M0
IV T1 N2 M0
IV T2 N2 M0
IV T3 N2 M0
IV Any T N3 M0
IV T4 Any N M0
IV Any T Any N M1