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TNM and Stage Groupings > Gallbladder
Gallbladder
Primary Tumor (T)
| T Category |
Stage Category Definitions |
| TX |
Primary tumor cannot be assessed |
| T0 |
No evidence of primary tumor |
| Tis |
Carcinoma in situ |
| T1 |
Tumor invades lamina propria or muscular layer |
| T1a |
Tumor invades lamina propria |
| T1b |
Tumor invades muscular layer |
| T2 |
Tumor invades perimuscular connective tissue; no extension beyond serosa or
into liver |
| T3 |
Tumor perforates the serosa (visceral peritoneum) and/or directly invades the
liver and/or one other adjacent organ or structure, such as the stomach,
duodenum, colon, pancreas, omentum, or extrahepatic bile ducts |
| T4 |
Tumor invades main portal vein or hepatic artery or invades two or more
extrahepatic organs or structures |
Regional Lymph Nodes (N)
| N Category |
Stage Category Definitions |
| NX |
Regional lymph nodes cannot be assessed |
| N0 |
No regional lymph node metastasis |
| N1 |
Metastases to nodes along the cystic duct, common bile duct, hepatic artery,
and/or portal vein. |
| N2 |
Metastases to periaortic, pericaval, superior mesentery artery and/or celiac
artery lymph nodes |
Distant Metastasis (M)
| M Category |
Stage Category Definitions |
| M1 |
Distant metastasis |
No distant metastasis (no pathologic M0; use clinical M to complete stage group)
Anatomic Stage/Prognostic Groups
| Stage |
T |
N |
M |
| 0 |
Tis |
N0 |
M0 |
| I |
T1 |
N0 |
M0 |
| II |
T2 |
N0 |
M0 |
| IIIA |
T3 |
N0 |
M0 |
| IIIB |
T1-3 |
N1 |
M0 |
| IVA |
T4 |
N0-1 |
M0 |
| IVB |
Any T |
N2 |
M0 |
| IVB |
Any T |
Any N |
M1 |
