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Gastrointestinal Stromal Tumor

Primary Tumor (T)
T Category Stage Category Definitions
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
T1 Tumor 2 cm or less
T2 Tumor more than 2 cm but not more than 5 cm
T3 Tumor more than 5 cm but not more than 10 cm
T4 Tumor more than 10 cm in greatest dimension

Regional Lymph Nodes (N)
N Category Stage Category Definitions
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Regional lymph node metastasis

Distant Metastasis (M)
M Category Stage Category Definitions
M1 Distant metastasis
M1a Lung
M1b Other distant sites
No distant metastasis (no pathologic M0; use clinical M to complete stage group)

Anatomic Stage/Prognostic Groups - Gastric GIST
Stage T N M Mitotic Rate
IA T1 or T2 N0 M0 Low
IB T3 N0 M0 Low
II T1 N0 M0 High
II T2 N0 M0 High
II T4 N0 M0 Low
IIIA T3 N0 M0 High
IIIB T4 N0 M0 High
IV Any T N1 M0 Any rate
IV Any T Any N M1 Any rate
Anatomic Stage/Prognostic Groups - Small Intestinal GIST
Stage T N M Mitotic Rate
IA T1 or T2 N0 M0 Low
II T3 N0 M0 Low
IIIA T1 N0 M0 High
IIIA T4 N0 M0 Low
IIIB T2 N0 M0 High
IIIB T3 N0 M0 High
IIIB T4 N0 M0 High
IV Any T N1 M0 Any rate
IV Any T Any N M1 Any rate
Also to be used for esophagus, colorectal, and peritoneum