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TNM and Stage Groupings > Liver
Liver
Primary Tumor (T)
| T Category |
Stage Category Definitions |
| TX |
Primary tumor cannot be assessed |
| T0 |
No evidence of primary tumor |
| T1 |
Solitary tumor without vascular invasion |
| T2 |
Solitary tumor with vascular invasion or multiple tumors none more than 5 cm |
| T3a |
Multiple tumors more than 5 cm |
| T3b |
Single tumor or multiple tumors of any size involving a major branch of the
portal vein or hepatic vein |
| T4 |
Tumor(s) with direct invasion of adjacent organs other than the gallbladder or
with perforation of visceral peritoneum. |
Regional Lymph Nodes (N)
| N Category |
Stage Category Definitions |
| NX |
Regional lymph nodes cannot be assessed |
| N0 |
No regional lymph node metastasis |
| N1 |
Regional lymph node metastasis |
Distant Metastasis (M)
| M Category |
Stage Category Definitions |
| M1 |
Distant metastasis |
No distant metastasis (no pathologic M0; use clinical M to complete stage group)
Anatomic Stage/Prognostic Groups
| Stage |
T |
N |
M |
| I |
T1 |
N0 |
M0 |
| II |
T2 |
N0 |
M0 |
| IIIA |
T3a |
N0 |
M0 |
| IIIB |
T3b |
N0 |
M0 |
| IIIC |
T4 |
N0 |
M0 |
| IVA |
Any T |
N1 |
M0 |
| IVB |
Any T |
Any N |
M1 |
