Pleural Mesothelioma
| T Category | Stage Category Definitions |
|---|---|
| TX | Primary tumor cannot be assessed |
| T0 | No evidence of primary tumor |
| T1 | Tumor limited to the ipsilateral parietal pleura with or without mediastinal pleura and with or without diaphragmatic pleural involvement |
| T1a | No involvement of the visceral pleura |
| T1b | Tumor also involving the visceral pleura |
| T2 | Tumor involving each of the ipsilateral pleural surfaces (parietal, mediastinal,
diaphragmatic, and visceral pleura) with at least one of the following features: ‧ involvement of diaphragmatic muscle ‧ extension of tumor from visceral pleura into the underlying pulmonary parenchyma |
| T3 | Locally advanced but potentially resectable tumor Tumor involving all of the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral pleura) with at least one of the following features: ‧ involvement of the endothoracic fascia ‧ extension into the mediastinal fat ‧ solitary, completely resectable focus of tumor extending into the soft tissues of the chest wall ‧ non-transmural involvement of the pericardium |
| T4 | Locally advanced technically unresectable tumor Tumor involving all of the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral pleura) with at least one of the following features: ‧ diffuse extension or multifocal masses of tumor in the chest wall, with or without associated rib destruction ‧ direct transdiaphragmatic extension of tumor to the peritoneum ‧ direct extension of tumor to the contralateral pleura ‧ direct extension of tumor to mediastinal organs ‧ direct extension of tumor into the spine ‧ tumor extending through to the internal surface of the pericardium with or without a pericardial effusion; or tumor involving the myocardium |
| N Category | Stage Category Definitions |
|---|---|
| NX | Regional lymph nodes cannot be assessed |
| N0 | No regional lymph node metastases |
| N1 | Metastases in the ipsilateral bronchopulmonary or hilar lymph nodes |
| N2 | Metastases in the subcarinal or the ipsilateral mediastinal lymph nodes including the ipsilateral internal mammary and peridiaphragmatic nodes |
| N3 | Metastases in the contralateral mediastinal, contralateral internal mammary, ipsilateral or contralateral supraclavicular lymph nodes |
| M Category | Stage Category Definitions |
|---|---|
| M1 | Distant metastasis |
| Stage | T | N | M |
|---|---|---|---|
| I | T1 | N0 | M0 |
| IA | T1a | N0 | M0 |
| IB | T1b | N0 | M0 |
| II | T2 | N0 | M0 |
| III | T1, T2 | N1 | M0 |
| III | T1, T2 | N2 | M0 |
| III | T3 | N0, N1, N2 | M0 |
| IV | T4 | Any N | M0 |
| IV | Any T | N3 | M0 |
| IV | Any T | Any N | M1 |
