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Mucosal Melanoma of the Head and Neck

Primary Tumor (T)
T Category Stage Category Definitions
T3 Mucosal disease
T4a Moderately advanced disease
Tumor involving deep soft tissue, cartilage, bone, or overlying skin.
T4b Very advanced disease
Tumor involving brain, dura, skull base, lower cranial nerves (IX, X, XI, XII), masticator space, carotid artery, prevertebral space, or mediastinal structures

Regional Lymph Nodes (N)
N Category Stage Category Definitions
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Regional lymph node metastasis present

Distant Metastasis (M)
M Category Stage Category Definitions
M1 Distant metastasis
No distant metastasis (no pathologic M0; use clinical M to complete stage group)

Anatomic Stage/Prognostic Groups
Stage T N M
III T3 N0 M0
IVA T4a N0 M0
IVA T3-T4a N1 M0
IVB T4b Any N M0
IVC Any T Any N M1