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Ocular Adnexal Lymphoma

Primary Tumor (T)
T Category Stage Category Definitions
TX Lymphoma extent not specified
T0 No evidence of lymphoma
T1 Lymphoma involving the conjunctiva alone without orbital involvement
T1a Bulbar conjunctiva only
T1b Palpebral conjunctiva +/- fornix +/- caruncle
T1c Extensive conjunctival involvement
T2 Lymphoma with orbital involvement +/- any conjunctival involvement
T2a Anterior orbital involvement (+/- conjunctival involvement)
T2b Anterior orbital involvement (+/- conjunctival involvement + lacrimal involvement)
T2c Posterior orbital involvement (+/- conjunctival involvement +/- anterior involvement and +/- any extraocular muscle involvement)
T2d Nasolacrimal drainage system involvement (+/- conjunctival involvement but not including nasopharynx)
T3 Lymphoma with pre-septal eyelid involvement (defined above) +/- orbital involvement +/- any conjunctival involvement
T4 Orbital adnexal lymphoma extending beyond orbit to adjacent structures such as bone and brain
T4a Involvement of nasopharynx
T4b Osseous involvement (including periosteum)
T4c Involvement of maxillofacial, ethmoidal and/or frontal sinuses
T4d Intracranial spread

Regional Lymph Nodes (N)
N Category Stage Category Definitions
NX Regional lymph nodes cannot be assessed
N0 No evidence of lymph node involvement
N1 Involvement of ipsilateral regional lymph nodes*
N2 Involvement of contra lateral or bilateral regional lymph nodes *
N3 Involvement of peripheral lymph nodes not draining ocular adnexal region
N4 Involvement of central lymph nodes
* The regional lymph nodes included preauricular (parotid), submandibular, and cervical

Distant Metastasis (M)
M Category Stage Category Definitions
M1a Noncontiguous involvement of tissues or organs external to the ocular adnexa (e.g., parotid glands, submandibular gland, lung, liver, spleen, kidney, breast, etc.)
M1b Lymphomatous involvement of the bone marrow
M1c Both M1a and M1b involvement
No evidence of involvement of other extranodal sites (no pathologic M0; use clinical M to complete stage group)

Anatomic Stage/Prognostic Groups
Stage T N M
No stage grouping is presently recommended.