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TNM and Stage Groupings > Perihilar Bile Duct
Perihilar Bile Duct
Primary Tumor (T)
| T Category |
Stage Category Definitions |
| TX |
Primary tumor cannot be assessed |
| T0 |
No evidence of primary tumor |
| Tis |
Carcinoma in situ |
| T1 |
Tumor confined to the bile duct, with extension up to the muscle layer or fibrous
tissue |
| T2a |
Tumor invades beyond the wall of the bile duct to surrounding adipose tissue |
| T2b |
Tumor invades adjacent hepatic parenchyma |
| T3 |
Tumor invades unilateral branches of the portal vein or hepatic artery |
| T4 |
Tumor invades main portal vein or its branches bilaterally; or the common
hepatic artery; or the second-order biliary radicals bilaterally; or unilateral
second-order biliary radicals with contralateral portal vein or hepatic artery
involvement |
Regional Lymph Nodes (N)
| N Category |
Stage Category Definitions |
| NX |
Regional lymph nodes cannot be assessed |
| N0 |
No regional lymph node metastasis |
| N1 |
Regional lymph node metastasis (including nodes along the cystic duct,
common bile duct, hepatic artery, and portal vein) |
| N2 |
Metastasis to periaortic, pericaval, superior mesentery artery, and/or celiac
artery lymph nodes |
Distant Metastasis (M)
| M Category |
Stage Category Definitions |
| M1 |
Distant metastasis |
No distant metastasis (no pathologic M0; use clinical M to complete stage group)
Anatomic Stage/Prognostic Groups
| Stage |
T |
N |
M |
| 0 |
Tis |
N0 |
M0 |
| I |
T1 |
N0 |
M0 |
| II |
T2a-b |
N0 |
M0 |
| IIIA |
T3 |
N0 |
M0 |
| IIIB |
T1-3 |
N1 |
M0 |
| IVA |
T4 |
N0-1 |
M0 |
| IVB |
Any T |
N2 |
M0 |
| IVB |
Any T |
Any N |
M1 |
