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Renal Pelvis and Ureter

Primary Tumor (T)
T Category Stage Category Definitions
TX Primary tumor cannot be assessed
T0 No evidence of primary tumor
Ta Papillary noninvasive carcinoma
Tis Carcinoma in situ
T1 Tumor invades subepithelial connective tissue
T2 Tumor invades the muscularis
T3 (For renal pelvis only) Tumor invades beyond muscularis into peripelvic fat or the renal parenchyma T3.
(For ureter only) Tumor invades beyond muscularis into periureteric fat
T4 Tumor invades adjacent organs, or through the kidney into the perinephric fat

Regional Lymph Nodes (N)
N Category Stage Category Definitions
NX Regional lymph nodes cannot be assessed
N0 No regional lymph node metastasis
N1 Metastasis in a single lymph node, 2 cm or less in greatest dimension
N2 Metastasis in a single lymph node, more than 2 cm but not more than 5 cm in greatest dimension; or multiple lymph nodes, none more than 5 cm in greatest dimension
N3 Metastasis in a lymph node, more than 5 cm in greatest dimension
*Note: Laterality does not affect the N classification

Distant Metastasis (M)
M Category Stage Category Definitions
M1 Distant metastasis
No distant metastasis (no pathologic M0; use clinical M to complete stage group)

Anatomic Stage/Prognostic Groups
Stage T N M
0a Ta N0 M0
0is Tis N0 M0
I T1 N0 M0
II T2 N0 M0
III T3 N0 M0
IV T4 N0 M0
IV Any T N1 M0
IV Any T N2 M0
IV Any T N3 M0
IV Any T Any N M1