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TNM and Stage Groupings > Retinoblastoma
Retinoblastoma
Primary Tumor (T)
| T Category |
Stage Category Definitions |
| pTX |
Primary tumor cannot be assessed |
| pT0 |
No evidence of primary tumor |
| pT1 |
Tumor confined to eye with no optic nerve or choroidal invasion. |
| pT2 |
Tumor with minimal optic nerve and/or choroidal invasion |
| pT2a |
Tumor superficially invades optic nerve head but does not extend past lamina
cribrosa or tumor exhibits focal choroidal invasion. |
| pT2b |
Tumor superficially invades optic nerve head but does not extend past lamina
cribrosa and exhibits focal choroidal invasion. |
| pT3 |
Tumor with significant optic nerve and/or choroidal invasion |
| pT3a |
Tumor invades optic nerve past lamina cribrosa but not to surgical resection line
or tumor exhibits massive choroidal invasion. |
| pT3b |
Tumor invades optic nerve past lamina cribrosa but not to surgical resection line
and exhibits massive choroidal invasion. |
| pT4 |
Tumor invades optic nerve to resection line or exhibits extraocular extension
elsewhere. |
| pT4a |
Tumor invades optic nerve to resection line but no extraocular extension
identified |
| pT4b |
Tumor invades optic nerve to resection line and extraocular extension identified |
Regional Lymph Nodes (N)
| N Category |
Stage Category Definitions |
| NX |
Regional lymph nodes cannot be assessed |
| N0 |
No regional lymph node involvement |
| N1 |
Regional lymph node involvement (preauricular, cervical, submandibular) |
| N2 |
Distant lymph node involvement |
Distant Metastasis (M)
| M Category |
Stage Category Definitions |
| M1 |
Metastasis to sites other than CNS. |
| M1a |
Single lesion. |
| M1b |
Multiple lesions. |
| M1c |
CNS metastasis. |
| M1d |
Discrete mass(es) without leptomeningeal and/or CSF involvement. |
| M1e |
Leptomeningeal and/or CSF involvement. |
No distant metastasis (no pathologic M0; use clinical M to complete stage group)
Anatomic Stage/Prognostic Groups
| Stage |
T |
N |
M |
|
|
|
|
No stage grouping is presently recommended
