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TNM and Stage Groupings > Small Intestine
Small Intestine
Primary Tumor (T)
| T Category |
Stage Category Definitions |
| TX |
Primary tumor cannot be assessed |
| T0 |
No evidence of primary tumor |
| Tis |
Carcinoma in situ |
| T1a |
Tumor invades lamina propria |
| T1b |
Tumor invades submucosa |
| T2 |
Tumor invades muscularis propria |
| T3 |
Tumor invades through the muscularis propria into the subserosa or into the
nonperitonealized perimuscular tissue (mesentery or retroperitoneum) with
extension 2 cm or less* |
| T4 |
Tumor perforates the visceral peritoneum or directly invades other organs or
structures (includes other loops of small intestine, mesentery, or
retroperitoneum more than 2 cm, and abdominal wall by way of serosa; for
duodenum only, invasion of pancreas or bile duct) |
*The nonperitonealized perimuscular tissue is, for jejunum and ileum, part of the
mesentery and, for duodenum in areas where serosa is lacking, part of the
interface with the pancreas.
Regional Lymph Nodes (N)
| N Category |
Stage Category Definitions |
| NX |
Regional lymph nodes cannot be assessed |
| N0 |
No regional lymph node metastasis |
| N1 |
Metastasis in 1 to 3 regional lymph nodes |
| N2 |
Metastasis in 4 or more regional lymph nodes |
Distant Metastasis (M)
| M Category |
Stage Category Definitions |
| M1 |
Distant metastasis |
No distant metastasis (no pathologic M0; use clinical M to complete stage group)
Anatomic Stage/Prognostic Groups
| Stage |
T |
N |
M |
| 0 |
Tis |
N0 |
M0 |
| I |
T1 |
N0 |
M0 |
| I |
T2 |
N0 |
M0 |
| IIA |
T3 |
N0 |
M0 |
| IIB |
T4 |
N0 |
M0 |
| IIIA |
Any T |
N1 |
M0 |
| IIIB |
Any T |
N2 |
M0 |
| IV |
Any T |
Any N |
M1 |
