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TNM and Stage Groupings > Urethra
Urethra
Primary Tumor (T) (male and female)
| T Category |
Stage Category Definitions |
| TX |
Primary tumor cannot be assessed |
| T0 |
No evidence of primary tumor |
| Ta |
Non-invasive papillary, polypoid, or verrucous carcinoma |
| Tis |
Carcinoma in situ |
| T1 |
Tumor invades subepithelial connective tissue |
| T2 |
Tumor invades any of the following: corpus spongiosum, prostate, periurethral
muscle |
| T3 |
Tumor invades any of the following: corpus cavernosum, beyond prostatic
capsule, anterior vagina, bladder neck |
| T4 |
Tumor invades other adjacent organs |
Primary Tumor (T ) - Urothelial Carcinoma of the Prostate
| T Category |
Stage Category Definitions |
| Tis pu |
Carcinoma in situ, involvement of the prostatic urethra |
| Tis pd |
Carcinoma in situ, involvement of the prostatic ducts |
| T1 |
Tumor invades urethral subepithelial connective tissue |
| T2 |
Tumor invades any of the following: prostatic stroma, corpus spongiosum,
periurethral muscle |
| T3 |
Tumor invades any of the following: corpus cavernosum, beyond prostatic
capsule, bladder neck (extraprostatic extension) |
| T4 |
Tumor invades other adjacent organs (invasion of the bladder) |
Regional Lymph Nodes (N)
| N Category |
Stage Category Definitions |
| NX |
Regional lymph nodes cannot be assessed |
| N0 |
No regional lymph node metastasis |
| N1 |
Metastasis in a single lymph node 2 cm or less in greatest dimension |
| N2 |
Metastasis in a single node more than 2 cm in greatest dimension, or in multiple
nodes |
Distant Metastasis (M)
| M Category |
Stage Category Definitions |
| M1 |
Distant metastasis |
No distant metastasis (no pathologic M0; use clinical M to complete stage group)
Anatomic Stage/Prognostic Groups
| Stage |
T |
N |
M |
| 0a |
Ta |
N0 |
M0 |
| 0is |
Tis |
N0 |
M0 |
| 0is |
Tis pu |
N0 |
M0 |
| 0is |
Tis pd |
N0 |
M0 |
| I |
T1 |
N0 |
M0 |
| II |
T2 |
N0 |
M0 |
| III |
T1 |
N1 |
M0 |
| III |
T2 |
N1 |
M0 |
| III |
T3 |
N0 |
M0 |
| III |
T3 |
N1 |
M0 |
| IV |
T4 |
N0 |
M0 |
| IV |
T4 |
N1 |
M0 |
| IV |
Any T |
N2 |
M0 |
| IV |
Any T |
Any N |
M1 |