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WHO histological classification of odontogenic tumors

Malignant tumors

Odontogenic carcinomas

Metastasizing (malignant) ameloblastoma - ICD-O 9310/3
Ameloblastic carcinoma - primary type - ICD-O 9270/3
Ameloblastic carcinoma - secondary type (dedifferentiated), intraosseous - ICD-O 9270/3
Ameloblastic carcinoma - secondary type (dedifferentiated), peripheral - ICD-O 9270/3
Primary intraosseous squamous cell carcinoma - solid type - ICD-O 9270/3
Primary intraosseous squamous cell carcinoma derived from keratocystic odontogenic tumor - ICD-O 9270/3
Primary intraosseous squamous cell carcinoma derived from odontogenic cysts - ICD-O 9270/3
Clear cell odontogenic carcinoma - ICD-O 9341/3
Ghost cell odontogenic carcinoma - ICD-O 9302/3

Odontogenic sarcomas

Ameloblastic fibrosarcoma - ICD-O 9330/3
Ameloblastic fibrodentino-and fibro-odontosarcoma - ICD-O 9290/3

Benign tumors

Odontogenic epithelium with mature, fibrous stroma without odontogenic ectomesenchyme

Ameloblastoma, solid / multicystic type - ICD-O 9310/0
Ameloblastoma, extraosseous / peripheral type - ICD-O 9310/0
Ameloblastoma, desmoplastic type - ICD-O 9310/0
Ameloblastoma, unicystic type - ICD-O 9310/0
Squamous odontogenic tumor - ICD-O 9312/0
Calcifying epithelial odontogenic tumor - ICD-O 9340/0
Adenomatoid odontogenic tumor - ICD-O 9300/0
Keratocystic odontogenic tumor - ICD-O 9270/0

Odontogenic epithelium with odontogenic ectomesenchyme, with or without hard tissue formation

Ameloblastic fibroma - ICD-O 9330/0
Ameloblastic fibrodentinoma - ICD-O 9271/0
Ameloblastic fibro-odontoma - ICD-O 9290/0
Odontoma - ICD-O 9280/0

Odontoma, complex type - ICD-O 9282/0
Odontoma, compound type - ICD-O 9281/0

Odontoameloblastoma - ICD-O 9311/0
Calcifying cystic odontogenic tumor - ICD-O 9301/0
Dentinogenic ghost cell tumor - ICD-O 9302/0

Mesenchyme and/or odontogenic ectomesenchyme with or without odontogenic epithelium

Odontogenic fibroma - ICD-O 9321/0
Odontogenic myxoma / myxofibroma - ICD-O 9320/0
Cementoblastoma - ICD-O 9273/0

Bone-related lesions

Ossifying fibroma - ICD-O 9262/0
Fibrous dysplasia
Osseous dysplasia
Central giant cell lesion (granuloma)
Cherubism
Aneurysmal bone cyst
Simple bone cyst

Other tumors

Melanotic neuroectodermal tumor of infancy - ICD-O 9363/0