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WHO histological classification of tumors of the ovary

Surface epithelial-stromal tumors

Serous tumors

Malignant

Serous adenocarcinoma - ICD-O 8441/3
Surface papillary adenocarcinoma - ICD-O 8461/3
Adenocarcinofibroma (malignant adenofibroma) - ICD-O 9014/3

Serous borderline tumor - ICD-O 8442/1

Papillary cystic tumor - ICD-O 8462/1
Surface papillary tumor - ICD-O 8463/1
Serous borderline adenofibroma and cystadenofibroma - ICD-O 9014/1

Benign

Serous cystadenoma - ICD-O 8441/0
Serous papillary cystadenoma - ICD-O 8460/0
Serous surface papilloma - ICD-O 8461/0
Serous adenofibroma and cystadenofibroma - ICD-O 9014/0

Mucinous tumors

Malignant

Mucinous adenocarcinoma - ICD-O 8480/3
Mucinous cystadenocarcinofibroma (malignant adenofibroma) - ICD-O 9015/3

Mucinous borderline tumor - ICD-O 8472/1

Mucinous borderline tumor, intestinal type
Mucinous borderline tumor, endocervical-like

Benign

Mucinous cystadenoma - ICD-O 8470/0
Mucinous adenofibroma and cystadenofibroma - ICD-O 9015/0

Mucinous cystic tumor with mural nodules
Mucinous cystic tumor with pseudomyxoma peritonei - ICD-O 8480/3

Endometrioid tumors including variants with squamous differentiation

Malignant

Endometrioid adenocarcinoma, not otherwise specified - ICD-O 8380/3
Variant with squamous differentiation - ICD-O 8570/3
Ciliated variant - ICD-O 8383/3
Oxyphilic variant - ICD-O 8290/3
Secretory variant - ICD-O 8382/3
Adenocarcinofibroma (malignant adenofibroma) - ICD-O 8381/3
Malignant mullerian mixed tumor (carcinosarcoma) - ICD-O 8950/3
Adenosarcoma - ICD-O 8933/3
Endometrioid stromal sarcoma - ICD-O 8930/3
Endometrioid stromal sarcoma (low grade) - ICD-O 8931/3
Undifferentiated ovarian sarcoma - ICD-O 8805/3

Endometrioid borderline tumor - ICD-O 8380/1

Cystic tumor - ICD-O 8380/1
Adenofibroma and cystadenofibroma - ICD-O 8381/1

Benign

Cystadenoma - ICD-O 8380/0
Adenofibroma and cystadenofibroma - ICD-O 8381/0

Clear cell tumors

Malignant

Clear cell adenocarcinoma - ICD-O 8310/3
Clear cell adenocarcinofibroma (malignant adenofibroma) - ICD-O 8313/3

Borderline clear cell adenofibromatous tumor

Clear cell tumor of borderline malignancy - ICD-O 8310/1
Cystic tumor - ICD-O 8310/1
Clear cell adenofibroma and cystadenofibroma of borderline malignancy - ICD-O 8313/1

Benign

Clear cell cystadenoma - ICD-O 8310/0
Clear cell adenofibroma and cystadenofibroma - ICD-O 8313/0

Transitional cell tumors

Malignant

Transitional cell carcinoma (non-Brenner type) - ICD-O 8120/3
Malignant Brenner tumor - ICD-O 9000/3

Borderline

Borderline Brenner tumor - ICD-O 9000/1
Proliferating variant - ICD-O 9000/1

Benign

Benign Brenner tumor - ICD-O 9000/0
Metaplastic variant - ICD-O 9000/0

Squamous cell tumors

Squamous cell carcinoma - ICD-O 8070/3
Epidermoid cyst

Mixed epithelial tumors (specify components)

Malignant mixed epithelial tumor - ICD-O 8323/3
Borderline mixed epithelial tumor - ICD-O 8323/1
Benign mixed epithelial tumor - ICD-O 8323/0

Undifferentiated and unclassified tumors

Undifferentiated carcinoma - ICD-O 8020/3
Adenocarcinoma, not otherwise specified (unclassified adenocarcinoma) - ICD-O 8140/3

Sex cord-stromal tumors

Granulosa-stromal cell tumors

Granulosa cell tumor group

Adult granulosa cell tumor - ICD-O 8620/1
Juvenile granulosa cell tumor - ICD-O 8622/1

Thecoma-fibroma group

Thecoma, not otherwise specified - ICD-O 8600/0

Typical - ICD-O 8600/0
Luteinizd thecoma - ICD-O 8601/0

Fibroma, NOS - ICD-O 8810/0
Cellular fibroma - ICD-O 8810/1
Fibrosarcoma - ICD-O 8810/3
Stromal tumor with minor sex cord elements - ICD-O 8593/1
Sclerosing stromal tumor - ICD-O 8602/0
Signet-ring stromal tumor
Unclassified (fibrothecoma)

Sertoli-stromal cell tumors

Sertoli-Leydig cell tumor group (androblastomas)

Well differentiated - ICD-O 8631/0
Of intermediate differentiation - ICD-O 8631/1

Variant with heterologous elements (specify type) - ICD-O 8634/1

Poorly differentiated (sarcomatoid) - ICD-O 8631/3

Variant with heterologous elements (specify type) - ICD-O 8634/3

Retiform - ICD-O 8633/1

Variant with heterologous elements (specify type) - ICD-O 8634/1

Sertoli cell tumor, NOS - ICD-O 8640/1
Stromal-Leydig cell tumor

Sex cord-stromal tumors of mixed or unclassified cell types

Sex cord tumor with annular tubules - ICD-O 8623/1
Variant associated with Peutz-Jeghers syndrome - ICD-O 8623/0
Gynandroblastoma (specify components) - ICD-O 8632/1
Sex cord-stromal tumor, unclassified - ICD-O 8590/1

Steroid cell tumors

Stromal luteoma - ICD-O 8610/0

Leydig cell tumor group

Hilus cell tumor - ICD-O 8660/0
Leydig cell tumor, non-hilar type - ICD-O 8650/1
Leydig cell tumor, not otherwise specified - ICD-O 8650/1?

Steroid cell tumor, not otherwise specified - ICD-O 8670/0

Well differentiated - ICD-O 8670/0
Malignant - ICD-O 8670/3

Germ cell tumors

Primitive germ cell tumors

Dysgerminoma - ICD-O 9060/3
Yolk sac tumor - ICD-O 9071/3

Polyvesicular vitelline tumor
Glandular variant
Hepatoid variant

Embryonal carcinoma - ICD-O 9070/3
Polyembryoma - ICD-O 9072/3
Non-gestational choriocarcinoma - ICD-O 9100/3
Mixed germ cell tumor (specify components) - ICD-O 9085/3

Biphasic or triphasic teratoma

Immature teratoma - ICD-O 9080/3
Mature teratoma - ICD-O 9080/0

Solid
Cystic teratoma - ICD-O 9080/0

Dermoid cyst - ICD-O 9084/0

Fetiform teratoma (homunculus)

Monodermal teratoma and somatic-type tumors associated with dermoid cysts

Thyroid tumor group

Struma ovarii

Benign - ICD-O 9090/0
Malignant (specify type) - ICD-O 9090/3

Carcinoid group

Insular - ICD-O 8240/3
Trabecular - ICD-O 8240/3
Mucinous carcinoid - ICD-O 8243/3
Strumal carcinoid - ICD-O 9091/1
Mixed

Neuroectodermal tumor group

Ependymoma - ICD-O 9391/3
Primitive neuroectodermal tumor - ICD-O 9473/3
Medulloepithelioma - ICD-O 9501/3
Glioblastoma multiforme - ICD-O 9440/3
Others

Teratoma with malignant transformation - ICD-O 9084/3
Carcinoma group

Squamous cell carcinoma - ICD-O 8070/3
Adenocarcinoma - ICD-O 8140/3
Others

Melanocytic group

Malignant melanoma - ICD-O 8720/3
Melanocytic nevus - ICD-O 8720/0

Sarcoma group (specify type)
Sebaceous tumor group

Sebaceous adenoma - ICD-O 8410/0
Sebaceous carcinoma - ICD-O 8410/3

Pituitary-type tumor group
Retinal anlage tumor group - ICD-O 9363/0
Others

Germ cell-sex cord-stromal tumors

Gonadoblastoma - ICD-O 9073/1

Variant with malignant germ cell tumor

Mixed germ cell-sex cord-stromal tumor

Variant with malignant germ cell tumor

Tumors of the rete ovarii

Rete ovarii adenocarcinoma - ICD-O 9110/3
Rete ovarii adenoma - ICD-O 9110/0
Cystadenoma
Cystadenofibroma

Miscellaneous tumors

Small cell carcinoma, hypercalcemic type - ICD-O 8041/3
Small cell carcinoma, pulmonary type - ICD-O 8041/3
Large cell neuroendocrine carcinoma - ICD-O 8013/3
Hepatoid carcinoma - ICD-O 8576/3
Ovarian malignant mesothelioma - ICD-O 9050/3
Wilms tumor - ICD-O 8960/3
Gestational choriocarcinoma - ICD-O 9100/3
Hydatidiform mole - ICD-O 9100/0
Adenoid cystic carcinoma - ICD-O 8200/3
Basal cell tumor - ICD-O 8090/1
Ovarian wolffian tumor - ICD-O 9110/1
Paraganglioma - ICD-O 8693/1
Myxoma - ICD-O 8840/0
Soft tissue tumors not specific to the ovary
Others

Tumor-like conditions

Luteoma of pregnancy
Stromal hyperthecosis
Stromal hyperplasia
Fibromatosis
Massive ovarian oedema
Others

Lymphoid and hematopoetic tumors

Malignant lymphoma (specify type)
Leukemia (specify type)
Plasmacytoma - ICD-O 9734/3

Secondary tumors