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WHO histological classification of tumors of the small intestine

Epithelial tumors

Adenoma - ICD-O 8140/0

Tubular - ICD-O 8211/0
Villous - ICD-O 8261/0
Tubulovillous - ICD-O 8263/0

Intraepithelial neoplasia (dysplasia) associated with chronic inflammatory diseases

Low-grade glandular intraepithelial neoplasia
High-grade glandular intraepithelial neoplasia

Carcinoma

Adenocarcinoma - ICD-O 8140/3
Mucinous adenocarcinoma - ICD-O 8480/3
Signet-ring cell carcinoma - ICD-O 8490/3
Small cell carcinoma - ICD-O 8041/3
Squamous cell carcinoma - ICD-O 8070/3
Adenosquamous carcinoma - ICD-O 8560/3
Medullary carcinoma - ICD-O 8510/3
Undifferentiated carcinoma - ICD-O 8020/3

Carcinoid (well differentiated endocrine neoplasm) - ICD-O 8240/3

Gastrin cell tumor, functioning (gastrinoma) - ICD-O 8153/1
or non-functioning
Somatostatin cell tumor - ICD-O 8156/1
EC-cell, serotonin-producing neoplasm - ICD-O 8241/3
L-cell, glucagon-like peptide and PP/PYY producing tumor

Mixed carcinoid-adenocarcinoma - ICD-O 8244/3
Gangliocytic paraganglioma - ICD-O 8683/0
Others

Non-epithelial tumors

Lipoma - ICD-O 8850/0
Leiomyoma - ICD-O 8890/0
Gastrointestinal stromal tumor - ICD-O 8936/1
Leiomyosarcoma - ICD-O 8890/3
Angiosarcoma - ICD-O 9120/3
Kaposi sarcoma - ICD-O 9140/3
Others

Malignant lymphomas

Immunoproliferative small intestinal disease (includes a-heavy chain disease) - ICD-O 9764/3
Western type B-cell lymphoma of MALT - ICD-O 9699/3
Mantle cell lymphoma - ICD-O 9673/3
Diffuse large B-cell lymphoma - ICD-O 9680/3
Burkitt lymphoma - ICD-O 9687/3
Burkitt-like / atypical Burkitt-lymphoma - ICD-O 9687/3
T-cell lymphoma - ICD-O 9702/3

enteropathy associated - ICD-O 9717/3
unspecified - ICD-O 9702/3

Others

Secondary tumors

Polyps

Hyperplastic (metaplastic)
Peutz-Jeghers
Juvenile